This work estimates the added burden of immediate (hours, days) and longer-term (weeks) exposure to PM2.5 from wildfire and non-wildfire sources on respiratory (COPD and asthma), cardiovascular (myocardial infarction and heart failure), and cerebrovascular (stroke and transient ischemic attack) emergency department (ED) visits and hospitalizations, and how these relationships are modified by social vulnerability factors (race and ethnicity, neighborhood deprivation, EJ community designation) across communities in California (represented by ~1300 zip codes).